Reliable Pan-Cancer Microsatellite Instability Assessment by Using Targeted Next-Generation Sequencing Data
نویسندگان
چکیده
منابع مشابه
Microsatellite instability detection by next generation sequencing.
BACKGROUND Microsatellite instability (MSI) is a useful phenotype in cancer diagnosis and prognosis. Nevertheless, methods to detect MSI status from next generation DNA sequencing (NGS) data are underdeveloped. METHODS We developed an approach to detect the MSI phenotype using NGS (mSINGS). The method was used to evaluate mononucleotide microsatellite loci that were incidentally sequenced aft...
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ژورنال
عنوان ژورنال: JCO Precision Oncology
سال: 2017
ISSN: 2473-4284
DOI: 10.1200/po.17.00084